Gold nanoparticles-based nanoconjugates for enhanced enzyme cascade and glucose sensing.

نویسندگان

  • Dongdong Zeng
  • Weijie Luo
  • Jiang Li
  • Huajie Liu
  • Hongwei Ma
  • Qing Huang
  • Chunhai Fan
چکیده

We have coupled gold nanoparticles with horseradish peroxidase (HRP) to assemble catalytic nanoconjugates (HRP-AuNPs) for glucose detection. We found that a proper mixing ratio of HRP/AuNPs can significantly improve catalytic activity for the cascade reaction, an effect arising from increased spatial coupling between enzymes. Such gold nanoparticle-based nanoconjugates are shown to be promising nanosensors for glucose.

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عنوان ژورنال:
  • The Analyst

دوره 137 19  شماره 

صفحات  -

تاریخ انتشار 2012